Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization

European journal of pain 2024 Aug;28(7):1069-1094.  doi: 10.1002/ejp.2251. Epub 2024 Feb 21. Sophie Clarke, Richard Rogers, Vishvarani Wanigasekera, Francesca Fardo, Hossein Pia, Zahra Nochi, Nicolas Macian, Vincent Leray, Nanna Brix Finnerup, Gisèle Pickering, André Mouraux, Andrea Truini , Rolf-Detlef Treede, Luis Garcia-Larrea, Irene Tracey Abstract Background and objective: Functional magnetic resonance imaging, in conjunction with models

An approach to the detection of pain from autonomic and cortical correlates

Clinical Neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2024 Aug 5:166:152-165.  doi: 10.1016/j.clinph.2024.07.018. Online ahead of print. F Chouchou, C Fauchon, C Perchet, L Garcia-Larrea  Abstract Objective: To assess the value of combining brain and autonomic measures to discriminate the subjective

Pain cues override identity cues in baby cries

iScience 2024 Jun 24;27(7):110375. doi: 10.1016/j.isci.2024.110375. eCollection 2024 Jul 19. Siloé Corvin, Camille Fauchon, Hugues Patural, Roland Peyron, David Reby, Frédéric Theunissen, Nicolas Mathevon  Abstract Baby cries can convey both static information related to individual identity and dynamic information related to the baby’s emotional and physiological state.

Focal changes in alpha oscillations during short-term memorization of pain: a high-density electroencephalogram study with source localization

The European journal of neuroscience 2024 May;59(10):2778-2791.  doi: 10.1111/ejn.16317. Epub 2024 Mar 21. Argitxu Caldichoury, Luis Garcia-Larrea, Maud Frot Abstract Memories of painful events constitute the basis for assessing patients’ pain. This study explores the brain oscillatory activity during short-term memorization of a

Discordance between pain specialists and patients on the perception of dependence on pain medication: A multi-center cross-sectional study

Therapie 2024 Apr 12:S0040-5957(24)00043-X doi: 10.1016/j.therap.2024.01.008. Online ahead of print. Anne Roussin, Zénab Cissé, Vanessa Rousseau, Guillaume Roche, Cécile Lestrade, Alexandre Cauchie, Noémie Delage, Anne Donnet, Elise Van Obberghen, Chantal Wood, Maryse Lapeyre-Mestre, Nathalie Cantagrel Abstract Aim: Patients with chronic non-cancer pain are referred to pain centres to improve their pain

Safety and efficacy of atogepant for the preventive treatment of episodic migraine in adults for whom conventional oral preventive treatments have failed (ELEVATE): a randomised, placebo-controlled, phase 3b trial

The Lancet Neurology 2024 Feb 13:S1474-4422(24)00025-5. doi: 10.1016/S1474-4422(24)00025-5.  Cristina Tassorelli, Krisztián Nagy, Patricia Pozo-Rosich, Michel Lanteri-Minet, Sara Sacco, Tomáš Nežádal, Hua Guo, Rosa De Abreu Ferreira, Giovanna Forero, Joel M Trugman Abstract Background: Atogepant, an oral calcitonin gene-related peptide receptor antagonist, has been approved for the preventive treatment of

Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice

PAIN 2024 Feb 1;165(2):470-486. doi: 10.1097/j.pain.0000000000003030. Ahmed Negm, Katharina Stobbe, Selma Ben Fradj, Clara Sanchez, Arnaud Landra-Willm, Margaux Richter, Lucile Fleuriot, Delphine Debayle, Emmanuel Deval, Eric Lingueglia, Carole Rovere, Jacques Noel   Abstract Lipid-rich diet is the major cause of obesity, affecting 13% of the worldwide adult population. Obesity is a

Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice

Pain 2024 Jan 1;165(1):192-201.  doi: 10.1097/j.pain.0000000000003012. Epub 2023 Aug 11. Aude Charron, Lucie Pepino, Pascale Malapert, Vincent Debrauwer, Francis Castets, Chiara Salio, Aziz Moqrich Abstract Decreased GABA levels in injury-induced loss of spinal inhibition are still under intense interest and debate. Here, we show that GAD67 haplodeficient

Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter

Clinical neurophysiology 2023 Dec:156:28-37.  doi: 10.1016/j.clinph.2023.08.022. Epub 2023 Oct 6. C Leone, G Di Pietro, Y Salman, E Galosi, G Di Stefano, O Caspani , L Garcia-Larrea, A Mouraux, R-D Treede, A Truini  Abstract Objective: The N13 component of somatosensory evoked potential (N13 SEP) represents the segmental response of cervical dorsal