Relevant factors for neurologists to define effectiveness of migraine preventive drugs and take decisions on treatment. My- LIFE European Delphi survey

European Journal of Pain 2021 Nov;25(10):2177-2189 doi: 10.1002/ejp.1831. Epub 2021 Jul 13. Patricia Pozo-Rosich, Raquel Gil-Gouveia, Anne Donnet, Anne-Christine Poole, Astrid Gendolla, Shazia Afridi, Rainel Sanchez-De la Rosa, Gisela M Terwindt, Cristina Tassorelli Abstract Background: Clinical guidelines agree that preventive treatment should be considered in patients with uncontrolled

Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels

The Journal of clinical investigation 2021 Nov 01;131(21):e142203. doi: 10.1172/JCI142203. Oana Chever, Sarah Zerimech, Paolo Scalmani, Louisiane Lemaire, Lara Pizzamiglio, Alexandre Loucif, Marion Ayrault, Martin Krupa, Mathieu Desroches, Fabrice Duprat, Isabelle Léna, Sandrine Cestèle, Massimo Mantegazza Abstract Spreading depolarizations (SDs) are involved in migraine, epilepsy, stroke, traumatic brain injury, and subarachnoid hemorrhage.

C-Jun N-Terminal Kinase Post-Translational Regulation of Pain-Related Acid-Sensing Ion Channels 1b and 3

The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Oct 20;41(42):8673-8685 doi: 10.1523/JNEUROSCI.0570-21.2021. Epub 2021 Aug 11. Clément Verkest , Sylvie Diochot, Eric Lingueglia, Anne Baron Abstract Neuronal proton-gated acid-sensing ion channels (ASICs) participate in the detection of

Episodic syndromes that may be associated with migraine: What adult neurologists need to know

Revue Neurologique 2021 Sep;177(7):773-778.doi: 10.1016/j.neurol.2021.07.002. Epub 2021 Aug 5. S Redon Abstract Four episodic syndromes are recognized in the current version of the International Classification of Headache Disorders (ICHD): cyclic vomiting syndrome (CVS); abdominal migraine; benign paroxysmal vertigo; benign paroxysmal

Revised guidelines of the French headache society for the diagnosis and management of migraine in adults. Part 3: Non-pharmacological treatment

Revue Neurologique 2021 Sep;177(7):753-759 G Demarquay, J Mawet, E Guégan-Massardier, S de Gaalon, A Donnet, P Giraud, M Lantéri-Minet, C Lucas, X Moisset, C Roos, D Valade, A Ducros Abstract The French Headache Society proposes updated French guidelines for the

Revised guidelines of the French headache society for the diagnosis and management of migraine in adults. Part 2: Pharmacological treatment

Revue Neurologique 2021 Sep;177(7):734-752. A Ducros, S de Gaalon, C Roos, A Donnet, P Giraud, E Guégan-Massardier, M Lantéri-Minet, C Lucas, J Mawet, X Moisset, D Valade, G Demarquay Abstract The French Headache Society proposes updated French guidelines for the

Revised guidelines of the French Headache Society for the diagnosis and management of migraine in adults. Part 1: Diagnosis and assessment

Revue Neurologique 2021 Sep;177(7):725-733. G Demarquay, X Moisset, M Lantéri-Minet, S de Gaalon, A Donnet , P Giraud, E Guégan-Massardier, C Lucas, J Mawet, C Roos, D Valade, A Ducro Abstract The French Headache Society proposes updated French guidelines for

TREK channel activation suppresses migraine pain phenotype

iScience 2021 Aug 8;24(9):102961 doi: 10.1016/j.isci.2021.102961. eCollection 2021 Sep 24. Pablo Ávalos Prado , Arnaud Landra-Willm , Clément Verkest  , Aurore Ribera  , Anne-Amandine Chassot  , Anne Baron  , Guillaume Sandoz. Abstract Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of