An ankyrin G-binding motif mediates TRAAK periodic localization at axon initial segments of hippocampal pyramidal neurons

Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 30;121(31):e2310120121.  doi: 10.1073/pnas.2310120121. Epub 2024 Jul 26. Virginia Luque-Fernández 1, Sam K Vanspauwen 1, Arnaud Landra-Willm 2 3 4, Emil Arvedsen 1, Maïlys Besquent 2 3 4, Guillaume Sandoz 2 3 4, Hanne B Rasmussen 1 Abstract The axon initial segment (AIS) is a critical

Efficacy of Atogepant in Chronic Migraine With and Without Acute Medication Overuse in the Randomized, Double-Blind, Phase 3 PROGRESS Trial

Neurology 2024 Jul 23;103(2):e209584.  doi: 10.1212/WNL.0000000000209584. Epub 2024 Jun 26. Peter J Goadsby, Deborah I Friedman, Dagny Holle-Lee, Genevieve Demarquay, Sait Ashina, Fumihiko Sakai, Brian Neel, Pranav Gandhi , Brett Dabruzzo, Jonathan H Smith, Yingyi Liu, Joel M Trugman Abstract Background and objectives: Atogepant is an oral, calcitonin gene-related peptide receptor antagonist approved

Pain cues override identity cues in baby cries

iScience 2024 Jun 24;27(7):110375. doi: 10.1016/j.isci.2024.110375. eCollection 2024 Jul 19. Siloé Corvin, Camille Fauchon, Hugues Patural, Roland Peyron, David Reby, Frédéric Theunissen, Nicolas Mathevon  Abstract Baby cries can convey both static information related to individual identity and dynamic information related to the baby’s emotional and physiological state.

Gut microbiota promotes pain chronicity in Myosin1A deficient male mice

Brain, Behavior, and Immunity 2024 Jul:119:750-766. doi: 10.1016/j.bbi.2024.05.010. Epub 2024 May 4. Ana Reynders, Z Anissa Jhumka, Stéphane Gaillard, Annabelle Mantilleri, Pascale Malapert, Karine Magalon, Anders Etzerodt, Chiara Salio, Sophie Ugolini, Francis Castets, Andrew J Saurin, Matteo Serino, Guillaume Hoeffel, Aziz Moqrich Abstract Chronic pain is a heavily debilitating condition and a huge socio-economic

Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons

Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 2;121(27):e2403777121. doi: 10.1073/pnas.2403777121. Epub 2024 Jun 25. Haoyi Qiu, Loïs S Miraucourt, Hugues Petitjean, Mengyi Xu, Catherine Theriault, Albena Davidova, Vanessa Soubeyre, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Philipa Levesque-Damphousse, Jennifer L Estall, Emmanuel Bourinet, Reza Sharif-Naeini Abstract