Patient Sex in Prescribing CGRP Receptor Antagonists for Migraine

JAMA Neurology JAMA Neurol. Published online February 26, 2024. doi:10.1001/jamaneurol.2023.5835 Michel Lanteri-Minet; Shuu-Jiun Wang; Paolo Martelletti To the Editor In a recent JAMA Neurology Viewpoint,1 Porreca and Dodick raised an important issue by discussing gender differences in outcomes of calcitonin

Safety and efficacy of atogepant for the preventive treatment of episodic migraine in adults for whom conventional oral preventive treatments have failed (ELEVATE): a randomised, placebo-controlled, phase 3b trial

The Lancet Neurology 2024 Feb 13:S1474-4422(24)00025-5. doi: 10.1016/S1474-4422(24)00025-5.  Cristina Tassorelli, Krisztián Nagy, Patricia Pozo-Rosich, Michel Lanteri-Minet, Sara Sacco, Tomáš Nežádal, Hua Guo, Rosa De Abreu Ferreira, Giovanna Forero, Joel M Trugman Abstract Background: Atogepant, an oral calcitonin gene-related peptide receptor antagonist, has been approved for the preventive treatment of

Improved Outcomes and Therapy Longevity after Salvage Using a Novel Spinal Cord Stimulation System for Chronic Pain: Multicenter, Observational, European Case Series

Journal of Clinical Medicine 2024 Feb 14;13(4):1079. doi: 10.3390/jcm13041079. Philippe Rigoard, Maxime Billot, Renaud Bougeard, Jose Emilio Llopis, Sylvie Raoul, Georgios Matis, Jan Vesper, Hayat Belaïd  Abstract Spinal cord stimulation (SCS) is proven to effectively relieve chronic neuropathic pain. However, some implanted patients may face loss of efficacy

Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice

PAIN 2024 Feb 1;165(2):470-486. doi: 10.1097/j.pain.0000000000003030. Ahmed Negm, Katharina Stobbe, Selma Ben Fradj, Clara Sanchez, Arnaud Landra-Willm, Margaux Richter, Lucile Fleuriot, Delphine Debayle, Emmanuel Deval, Eric Lingueglia, Carole Rovere, Jacques Noel   Abstract Lipid-rich diet is the major cause of obesity, affecting 13% of the worldwide adult population. Obesity is a

Examining the Type, Quality, and Content of Web-Based Information for People With Chronic Pain Interested in Spinal Cord Stimulation: Social Listening Study

Journal of Medical Internet Research 2024 Jan 30:26:e48599. doi: 10.2196/48599. Maarten Moens, Leen Van Doorslaer, Maxime Billot, Edgard Eeckman, Manuel Roulaud, Philippe Rigoard, Maaike Fobelets, Lisa Goudman  Abstract Background: The increased availability of web-based medical information has encouraged patients with chronic pain to seek health care information from

Gut dysbiosis in patients with chronic pain: a systematic review and meta-analysis

Frontiers in immunology 2024 Jan 30:15:1342833. doi: 10.3389/fimmu.2024.1342833. eCollection 2024. Lisa Goudman, Thomas Demuyser, Julie G Pilitsis, Maxime Billot, Manuel Roulaud, Philippe Rigoard, Maarten Moens  Abstract Introduction: Recent evidence supports the contribution of gut microbiota dysbiosis to the pathophysiology of rheumatic diseases, neuropathic pain, and neurodegenerative disorders. The

Productive art engagement in a hybrid format: effects on emotions of older adults during COVID-19 pandemic

Frontiers in Public Health 2024 Jan 26:12:1257411. doi: 10.3389/fpubh.2024.1257411. eCollection 2024. Magali Payne, Kevin Galery, Alexandra Plonka, Justine Lemaire, Alexandre Derreumaux, Roxane Fabre, Aurélie Mouton, Guillaume Sacco, Olivier Guerin, Valeria Manera, Philippe Robert, Olivier Beauchet, Auriane Gros   Abstract Introduction: Previous studies have shown benefits of productive art-activity on frail older adults’

Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice

Pain 2024 Jan 1;165(1):192-201.  doi: 10.1097/j.pain.0000000000003012. Epub 2023 Aug 11. Aude Charron, Lucie Pepino, Pascale Malapert, Vincent Debrauwer, Francis Castets, Chiara Salio, Aziz Moqrich Abstract Decreased GABA levels in injury-induced loss of spinal inhibition are still under intense interest and debate. Here, we show that GAD67 haplodeficient

Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter

Clinical neurophysiology 2023 Dec:156:28-37.  doi: 10.1016/j.clinph.2023.08.022. Epub 2023 Oct 6. C Leone, G Di Pietro, Y Salman, E Galosi, G Di Stefano, O Caspani , L Garcia-Larrea, A Mouraux, R-D Treede, A Truini  Abstract Objective: The N13 component of somatosensory evoked potential (N13 SEP) represents the segmental response of cervical dorsal