Revue Neurologique 2021 Sep;177(7):765-772.doi: 10.1016/j.neurol.2021.07.012. Epub 2021 Aug 9. L-M Terrier, D Fontaine Abstract Understanding intracranial nociceptive innervation is essential to understand the pathophysiology of headaches. Our knowledge about human intracranial nociception comes from sparse observations during neurosurgical procedures performed in
Revised guidelines of the French headache society for the diagnosis and management of migraine in adults. Part 3: Non-pharmacological treatment
Revue Neurologique 2021 Sep;177(7):753-759 G Demarquay, J Mawet, E Guégan-Massardier, S de Gaalon, A Donnet, P Giraud, M Lantéri-Minet, C Lucas, X Moisset, C Roos, D Valade, A Ducros Abstract The French Headache Society proposes updated French guidelines for the
Revised guidelines of the French headache society for the diagnosis and management of migraine in adults. Part 2: Pharmacological treatment
Revue Neurologique 2021 Sep;177(7):734-752. A Ducros, S de Gaalon, C Roos, A Donnet, P Giraud, E Guégan-Massardier, M Lantéri-Minet, C Lucas, J Mawet, X Moisset, D Valade, G Demarquay Abstract The French Headache Society proposes updated French guidelines for the
Revised guidelines of the French Headache Society for the diagnosis and management of migraine in adults. Part 1: Diagnosis and assessment
Revue Neurologique 2021 Sep;177(7):725-733. G Demarquay, X Moisset, M Lantéri-Minet, S de Gaalon, A Donnet , P Giraud, E Guégan-Massardier, C Lucas, J Mawet, C Roos, D Valade, A Ducro Abstract The French Headache Society proposes updated French guidelines for
Spinal cord stimulation for neuropathic pain
Revue Neurologique 2021 Sep;177(7):838-842.doi: 10.1016/j.neurol.2021.07.014. Epub 2021 Aug 9. D Fontaine Abstract Spinal cord stimulation (SCS) is used for more than 40years to treat localized chronic medically refractory neuropathic pain involving limb(s) and trunk. The most frequent indications remain complex
TREK channel activation suppresses migraine pain phenotype
iScience 2021 Aug 8;24(9):102961 doi: 10.1016/j.isci.2021.102961. eCollection 2021 Sep 24. Pablo Ávalos Prado , Arnaud Landra-Willm , Clément Verkest , Aurore Ribera , Anne-Amandine Chassot , Anne Baron , Guillaume Sandoz. Abstract Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of
Visual aura without headache as a pre-cluster symptom in episodic cluster headache: A report of two cases
Headache 2021 Juil 29;61(7):1140-1141. doi: 10.1111/head.14179. Epub 2021 Jul 29. Sylvain Redon, Marion Beltramone, Anne Donnet No abstract available PMID: 34325485 DOI: 10.1111/head.14179
The neurologist and the hydrops
Journal of vestibular research : equilibrium & orientation 2021;31(4):303-309.doi: 10.3233/VES-200790. Sylvain Redon , Maya Elzière, Anne Donnet Abstract The presence of endolymphatic hydrops has been studied in many neurological disorders. The pathophysiological mechanisms may involve CSF pressure variations, transmitted to the innear
Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine
PLoS computational biology 2021 Jul 27;17(7):e1009239. doi: 10.1371/journal.pcbi.1009239. eCollection 2021 Jul. Louisiane Lemaire, Mathieu Desroches, Martin Krupa, Lara Pizzamiglio, Paolo Scalmani , Massimo Mantegazza Abstract Loss of function mutations of SCN1A, the gene coding for the voltage-gated sodium channel NaV1.1, cause different types of epilepsy,
Fluorescent- and tagged-protoxin II peptides: potent markers of the Na v 1.7 channel pain target
British journal of pharmacology 2021 Jul;178(13):2632-2650 doi: 10.1111/bph.15453. Epub 2021 May 14. Jérôme Montnach , Stephan De Waard, Sébastien Nicolas, Sophie Burel, Nancy Osorio, Claude Zoukimian, Massimo Mantegazza, Rachid Boukaiba, Rémy Béroud, Michel Partiseti, Patrick Delmas, Céline Marionneau, Michel De Waard Abstract Background and purpose: Protoxin II (ProTx II) is a high