Improved Outcomes and Therapy Longevity after Salvage Using a Novel Spinal Cord Stimulation System for Chronic Pain: Multicenter, Observational, European Case Series

Journal of Clinical Medicine 2024 Feb 14;13(4):1079. doi: 10.3390/jcm13041079. Philippe Rigoard, Maxime Billot, Renaud Bougeard, Jose Emilio Llopis, Sylvie Raoul, Georgios Matis, Jan Vesper, Hayat Belaïd  Abstract Spinal cord stimulation (SCS) is proven to effectively relieve chronic neuropathic pain. However, some implanted patients may face loss of efficacy

Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice

PAIN 2024 Feb 1;165(2):470-486. doi: 10.1097/j.pain.0000000000003030. Ahmed Negm, Katharina Stobbe, Selma Ben Fradj, Clara Sanchez, Arnaud Landra-Willm, Margaux Richter, Lucile Fleuriot, Delphine Debayle, Emmanuel Deval, Eric Lingueglia, Carole Rovere, Jacques Noel   Abstract Lipid-rich diet is the major cause of obesity, affecting 13% of the worldwide adult population. Obesity is a

Examining the Type, Quality, and Content of Web-Based Information for People With Chronic Pain Interested in Spinal Cord Stimulation: Social Listening Study

Journal of Medical Internet Research 2024 Jan 30:26:e48599. doi: 10.2196/48599. Maarten Moens, Leen Van Doorslaer, Maxime Billot, Edgard Eeckman, Manuel Roulaud, Philippe Rigoard, Maaike Fobelets, Lisa Goudman  Abstract Background: The increased availability of web-based medical information has encouraged patients with chronic pain to seek health care information from

Gut dysbiosis in patients with chronic pain: a systematic review and meta-analysis

Frontiers in immunology 2024 Jan 30:15:1342833. doi: 10.3389/fimmu.2024.1342833. eCollection 2024. Lisa Goudman, Thomas Demuyser, Julie G Pilitsis, Maxime Billot, Manuel Roulaud, Philippe Rigoard, Maarten Moens  Abstract Introduction: Recent evidence supports the contribution of gut microbiota dysbiosis to the pathophysiology of rheumatic diseases, neuropathic pain, and neurodegenerative disorders. The

Productive art engagement in a hybrid format: effects on emotions of older adults during COVID-19 pandemic

Frontiers in Public Health 2024 Jan 26:12:1257411. doi: 10.3389/fpubh.2024.1257411. eCollection 2024. Magali Payne, Kevin Galery, Alexandra Plonka, Justine Lemaire, Alexandre Derreumaux, Roxane Fabre, Aurélie Mouton, Guillaume Sacco, Olivier Guerin, Valeria Manera, Philippe Robert, Olivier Beauchet, Auriane Gros   Abstract Introduction: Previous studies have shown benefits of productive art-activity on frail older adults’

Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice

Pain 2024 Jan 1;165(1):192-201.  doi: 10.1097/j.pain.0000000000003012. Epub 2023 Aug 11. Aude Charron, Lucie Pepino, Pascale Malapert, Vincent Debrauwer, Francis Castets, Chiara Salio, Aziz Moqrich Abstract Decreased GABA levels in injury-induced loss of spinal inhibition are still under intense interest and debate. Here, we show that GAD67 haplodeficient

Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter

Clinical neurophysiology 2023 Dec:156:28-37.  doi: 10.1016/j.clinph.2023.08.022. Epub 2023 Oct 6. C Leone, G Di Pietro, Y Salman, E Galosi, G Di Stefano, O Caspani , L Garcia-Larrea, A Mouraux, R-D Treede, A Truini  Abstract Objective: The N13 component of somatosensory evoked potential (N13 SEP) represents the segmental response of cervical dorsal

Application accuracy of Neuromate robot-guided deep brain stimulation procedures using the non-invasive frameless Neurolocate registration system

The International Journal of Medical Robotics and Computer Assisted Surgery 2023 Dec 13:e2610. doi: 10.1002/rcs.2610. Online ahead of print. Denys Fontaine , Fabien Almairac, Bruno Chiapello, Aurélie Leplus Abstract Objective: to measure the in vivo application accuracy of Neuromate robot-assisted

Generalizability of clinical trial efficacy results to a real-world population: An example in migraine prevention

The Journal of managed care and specialty pharmacy 2023 Dec;29(12):1321-1330.doi: 10.18553/jmcp.2023.29.12.1321. Marie-Ange Paget, Antje Tockhorn-Heidenreich, Mark Belger, Florence Chartier, Michel Lantéri-Minet Abstract Background: Health care decision makers are often concerned about the external validity of randomized controlled trials (RCTs), as their results may not