Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 30;121(31):e2310120121. doi: 10.1073/pnas.2310120121. Epub 2024 Jul 26. Virginia Luque-Fernández 1, Sam K Vanspauwen 1, Arnaud Landra-Willm 2 3 4, Emil Arvedsen 1, Maïlys Besquent 2 3 4, Guillaume Sandoz 2 3 4, Hanne B Rasmussen 1 Abstract The axon initial segment (AIS) is a critical
Efficacy of Atogepant in Chronic Migraine With and Without Acute Medication Overuse in the Randomized, Double-Blind, Phase 3 PROGRESS Trial
Neurology 2024 Jul 23;103(2):e209584. doi: 10.1212/WNL.0000000000209584. Epub 2024 Jun 26. Peter J Goadsby, Deborah I Friedman, Dagny Holle-Lee, Genevieve Demarquay, Sait Ashina, Fumihiko Sakai, Brian Neel, Pranav Gandhi , Brett Dabruzzo, Jonathan H Smith, Yingyi Liu, Joel M Trugman Abstract Background and objectives: Atogepant is an oral, calcitonin gene-related peptide receptor antagonist approved
Pain cues override identity cues in baby cries
iScience 2024 Jun 24;27(7):110375. doi: 10.1016/j.isci.2024.110375. eCollection 2024 Jul 19. Siloé Corvin, Camille Fauchon, Hugues Patural, Roland Peyron, David Reby, Frédéric Theunissen, Nicolas Mathevon Abstract Baby cries can convey both static information related to individual identity and dynamic information related to the baby’s emotional and physiological state.
Gut microbiota promotes pain chronicity in Myosin1A deficient male mice
Brain, Behavior, and Immunity 2024 Jul:119:750-766. doi: 10.1016/j.bbi.2024.05.010. Epub 2024 May 4. Ana Reynders, Z Anissa Jhumka, Stéphane Gaillard, Annabelle Mantilleri, Pascale Malapert, Karine Magalon, Anders Etzerodt, Chiara Salio, Sophie Ugolini, Francis Castets, Andrew J Saurin, Matteo Serino, Guillaume Hoeffel, Aziz Moqrich Abstract Chronic pain is a heavily debilitating condition and a huge socio-economic
Parvalbumin gates chronic pain through the modulation of firing patterns in inhibitory neurons
Proceedings of the National Academy of Sciences of the United States of America 2024 Jul 2;121(27):e2403777121. doi: 10.1073/pnas.2403777121. Epub 2024 Jun 25. Haoyi Qiu, Loïs S Miraucourt, Hugues Petitjean, Mengyi Xu, Catherine Theriault, Albena Davidova, Vanessa Soubeyre, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Philipa Levesque-Damphousse, Jennifer L Estall, Emmanuel Bourinet, Reza Sharif-Naeini Abstract
Somatotopy of the sensory thalamus: inputs from directional deep brain stimulation in pain patients
Annals of Clinical and Translational Neurology 2024 Jun 11.doi: 10.1002/acn3.52067. Aurelie Leplus, Petru Isan, Anne Balossier, Sarah Mouffok, Anne Donnet, Theodore Papadopoulo, Michel Lanteri-Minet, Jean Regis, Denys Fontaine Abstract Objective: The sensory ventroposterior (VP) thalamic nuclei display a mediolateral somatotopic organization (respectively head, arm, and leg). We studied
Efficacy and Safety of Erenumab in Participants With Episodic Migraine in Whom 2-4 Prior Preventive Treatments Had Failed: LIBERTY 3-Year Study
Neurology 2024 May;102(10):e209349. doi: 10.1212/WNL.0000000000209349. Epub 2024 Apr 26. Uwe Reuter, Peter J Goadsby, Michel D Ferrari, Gabriel Paiva Da Silva Lima, Subhayan Mondal, Jawed Kalim, Fatima Hasan, Shihua Wen, Michal Arkuszewski, Shaloo Pandhi, Tracy Stites, Michel Lanteri-Minet Abstract Background and objectives: The LIBERTY study assessed the efficacy and safety of erenumab
Trigeminal neuralgia
Nature reviews. Disease primers 2024 May 30;10(1):39. doi: 10.1038/s41572-024-00523-z. Sait Ashina, Carrie E Robertson, Anan Srikiatkhachorn, Giulia Di Stefano, Anne Donnet, Mojgan Hodaie, Mark Obermann, Marcela Romero-Reyes, Young Seok Park, Giorgio Cruccu, Lars Bendtsen Abstract Trigeminal neuralgia (TN) is a facial pain disorder characterized by intense and paroxysmal pain that
« Status trigeminal neuralgia »: Analysis of 39 cases and proposal for diagnostic criteria
Revue Neurologique (Paris) 2024 May 23:S0035-3787(24)00523-X. doi: 10.1016/j.neurol.2024.03.014. Online ahead of print. Z Poullet, S Redon, R Gravier-Dumonceau, A Donnet Abstract Objective: The aim of this descriptive study was to propose diagnostic criteria for acute exacerbation of trigeminal neuralgia (TN) based on the
Focal changes in alpha oscillations during short-term memorization of pain: a high-density electroencephalogram study with source localization
The European journal of neuroscience 2024 May;59(10):2778-2791. doi: 10.1111/ejn.16317. Epub 2024 Mar 21. Argitxu Caldichoury, Luis Garcia-Larrea, Maud Frot Abstract Memories of painful events constitute the basis for assessing patients’ pain. This study explores the brain oscillatory activity during short-term memorization of a