European Journal of Pain 2023 Sep;27(8):1006-1022. doi: 10.1002/ejp.2142. Epub 2023 Jun 6. Caroline Perchet, Koichi Hagiwara, Charbel Salameh, Luis Garcia-Larrea Abstract Background: Innocuous cooling of the skin activates cold-specific Aδ fibres, and hence, the recording of cold-evoked potentials (CEPs) may improve the objective assessment of
Non-invasive cortical stimulation for drug-resistant pain
Current opinion in supportive and palliative care 2023 Sep 1;17(3):142-149. doi: 10.1097/SPC.0000000000000654. Epub 2023 Jun 20. Luis Garcia-Larrea Abstract Purpose of review: Neuromodulation techniques are being increasingly used to alleviate pain and enhance quality of life. Non-invasive cortical stimulation was originally intended
Joint European Academy of Neurology-European Pain Federation-Neuropathic Pain Special Interest Group of the International Association for the Study of Pain guidelines on neuropathic pain assessment
European journal of neurology 2023 Aug;30(8):2177-2196. doi: 10.1111/ene.15831. Epub 2023 May 30. Andrea Truini, Katina Aleksovska, Christopher C Anderson, Nadine Attal, Ralf Baron, David L Bennett, Didier Bouhassira, Giorgio Cruccu, Elon Eisenberg, Elena Enax-Krumova, Karen Deborah Davis, Giulia Di Stefano, Nanna B Finnerup, Luis Garcia-Larrea, Ibrahem Hanafi, Simon Haroutounian, Pall Karlsson, Martin Rakusa, Andrew S C Rice, Juliane Sachau, Blair H
Personalized pain management: Ready for it?
Editorial – European Journal of Pain 2023 Oct;27(9):1043. doi: 10.1002/ejp.2168. Epub 2023 Aug 10. Luis Garcia-Larrea, Didier Bouhassira No abstract available PMID: 37565628 DOI: 10.1002/ejp.2168
Amygdala and anterior insula control the passage from nociception to pain
Cerebral cortex 2023 Mar 21;33(7):3538-3547. doi: 10.1093/cercor/bhac290. Juliette Gélébart, Luis Garcia-Larrea, Maud Frot Abstract Activation of the spinothalamic system does not always result in a subjective pain perception. While the cerebral network processing nociception is relatively well known, the one underlying its
Sympathetic skin response as an objective tool to estimate stimulus-associated arousal in a human model of hyperalgesia
Neurophysiologie clinique = Clinical neurophysiology 2022 Nov;52(6):436-445. doi: 10.1016/j.neucli.2022.10.002. Epub 2022 Oct 26. Charbel Salameh, Caroline Perchet, Koichi Hagiwara, Luis Garcia-Larrea Abstract Background: Pain is a private experience, whose assessment relies on subjective self-reporting. Inaccurate communication renders pain evaluation unreliable in individuals with alteration of
Better Fields or Currents? A Head-to-Head Comparison of Transcranial Magnetic (rTMS) Versus Direct Current Stimulation (tDCS) for Neuropathic Pain
Neurotherapeutics Randomized Controlled Trial . 2023 Jan;20(1):207-219. doi: 10.1007/s13311-022-01303-x. Epub 2022 Oct 20. Nathalie André-Obadia, Hasan Hodaj, Enkelejda Hodaj, Emile Simon, Chantal Delon-Martin, Luis Garcia-Larrea Abstract While high-frequency transcranial magnetic stimulation (HF-rTMS) is now included in the armamentarium to treat chronic neuropathic pain (NP), direct-current anodal
IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity
Trials 2022 Sep 5;23(1):739. doi: 10.1186/s13063-022-06431-5. Caterina Leone1, Giulia Di Stefano, Giuseppe Di Pietro, Petra Bloms-Funke, Irmgard Boesl , Ombretta Caspani , Sonya C Chapman, Nanna Brix Finnerup, Luis Garcia-Larrea, Tom Li, Marcus Goetz, André Mouraux, Bernhard Pelz, Esther Pogatzki-Zahn, Andreas Schilder, Erik Schnetter, Karin Schubart , Irene Tracey , Inaki F Troconiz, Hans Van Niel, Jose Miguel Vela Hernandez, Katy
Transcranial direct current stimulation of 3 cortical targets is no more effective than placebo as treatment for fibromyalgia: a double-blind sham-controlled clinical trial
Pain Randomized Controlled Trial 2022 Jul 1;163(7):e850-e861. doi: 10.1097/j.pain.0000000000002493. Epub 2021 Sep 23. Noelia Samartin-Veiga, Marina Pidal-Miranda, Alberto J González-Villar, Claire Bradley, Luis Garcia-Larrea, Anthony T O’Brien, María T Carrillo-de-la-Peña Abstract Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and the dorsolateral prefrontal cortex
Dissecting central post-stroke pain: a controlled symptom-psychophysical characterization
Brain communications 2022 Apr 5;4(3):fcac090. doi: 10.1093/braincomms/fcac090. eCollection 2022. Luciana Mendonça Barbosa, Valquíria Aparecida da Silva, Antônia Lilian de Lima Rodrigues, Diego Toledo Reis Mendes Fernandes, Rogério Adas Ayres de Oliveira, Ricardo Galhardoni, Lin Tchia Yeng , Jefferson Rosi Junior, Adriana Bastos Conforto, Leandro Tavares Lucato, Marcelo Delboni Lemos, Roland Peyron, Luis Garcia-Larrea, Manoel