Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization

European journal of pain 2024 Aug;28(7):1069-1094.  doi: 10.1002/ejp.2251. Epub 2024 Feb 21. Sophie Clarke, Richard Rogers, Vishvarani Wanigasekera, Francesca Fardo, Hossein Pia, Zahra Nochi, Nicolas Macian, Vincent Leray, Nanna Brix Finnerup, Gisèle Pickering, André Mouraux, Andrea Truini , Rolf-Detlef Treede, Luis Garcia-Larrea, Irene Tracey Abstract Background and objective: Functional magnetic resonance imaging, in conjunction with models

An approach to the detection of pain from autonomic and cortical correlates

Clinical Neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2024 Aug 5:166:152-165.  doi: 10.1016/j.clinph.2024.07.018. Online ahead of print. F Chouchou, C Fauchon, C Perchet, L Garcia-Larrea  Abstract Objective: To assess the value of combining brain and autonomic measures to discriminate the subjective

Focal changes in alpha oscillations during short-term memorization of pain: a high-density electroencephalogram study with source localization

The European journal of neuroscience 2024 May;59(10):2778-2791.  doi: 10.1111/ejn.16317. Epub 2024 Mar 21. Argitxu Caldichoury, Luis Garcia-Larrea, Maud Frot Abstract Memories of painful events constitute the basis for assessing patients’ pain. This study explores the brain oscillatory activity during short-term memorization of a

Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter

Clinical neurophysiology 2023 Dec:156:28-37.  doi: 10.1016/j.clinph.2023.08.022. Epub 2023 Oct 6. C Leone, G Di Pietro, Y Salman, E Galosi, G Di Stefano, O Caspani , L Garcia-Larrea, A Mouraux, R-D Treede, A Truini  Abstract Objective: The N13 component of somatosensory evoked potential (N13 SEP) represents the segmental response of cervical dorsal

Beyond trial-and-error: Individualizing therapeutic transcranial neuromodulation for chronic pain

European Journal of Pain 2023 Oct;27(9):1065-1083.  doi: 10.1002/ejp.2164. Epub 2023 Aug 19. Daniel Ciampi de Andrade, Luís García-Larrea Abstract Background and objective: Repetitive transcranial magnetic stimulation (rTMS) applied to the motor cortex provides supplementary relief for some individuals with chronic pain who are

Brain network functional connectivity changes in patients with anterior knee pain: a resting-state fMRI exploratory study

European radiology experimental 2023 Oct 9;7(1):60.  doi: 10.1186/s41747-023-00378-1. Vicente Sanchis-Alfonso, María Beser-Robles, Amadeo Ten-Esteve, Cristina Ramírez-Fuentes, Ángel Alberich-Bayarri, Raúl Espert, Luis García-Larrea, Luis Martí-Bonmatí  Abstract Background: This study investigates the functional brain connectivity in patients with anterior knee pain (AKP). While biomechanical models are frequently employed to investigate

Cold-evoked potentials in clinical practice: A head-to-head contrast with laser-evoked responses

European Journal of Pain 2023 Sep;27(8):1006-1022. doi: 10.1002/ejp.2142. Epub 2023 Jun 6. Caroline Perchet, Koichi Hagiwara, Charbel Salameh, Luis Garcia-Larrea Abstract Background: Innocuous cooling of the skin activates cold-specific Aδ fibres, and hence, the recording of cold-evoked potentials (CEPs) may improve the objective assessment of