Somatotopy of the sensory thalamus: inputs from directional deep brain stimulation in pain patients

Annals of Clinical and Translational Neurology 2024 Jun 11.doi: 10.1002/acn3.52067.  Aurelie Leplus, Petru Isan, Anne Balossier, Sarah Mouffok, Anne Donnet, Theodore Papadopoulo, Michel Lanteri-Minet, Jean Regis, Denys Fontaine Abstract Objective: The sensory ventroposterior (VP) thalamic nuclei display a mediolateral somatotopic organization (respectively head, arm, and leg). We studied

Efficacy and Safety of Erenumab in Participants With Episodic Migraine in Whom 2-4 Prior Preventive Treatments Had Failed: LIBERTY 3-Year Study

Neurology 2024 May;102(10):e209349.  doi: 10.1212/WNL.0000000000209349. Epub 2024 Apr 26. Uwe Reuter, Peter J Goadsby, Michel D Ferrari, Gabriel Paiva Da Silva Lima, Subhayan Mondal, Jawed Kalim, Fatima Hasan, Shihua Wen, Michal Arkuszewski, Shaloo Pandhi, Tracy Stites, Michel Lanteri-Minet    Abstract Background and objectives: The LIBERTY study assessed the efficacy and safety of erenumab

Trigeminal neuralgia

Nature reviews. Disease primers 2024 May 30;10(1):39. doi: 10.1038/s41572-024-00523-z. Sait Ashina, Carrie E Robertson, Anan Srikiatkhachorn, Giulia Di Stefano, Anne Donnet, Mojgan Hodaie, Mark Obermann, Marcela Romero-Reyes, Young Seok Park, Giorgio Cruccu, Lars Bendtsen Abstract Trigeminal neuralgia (TN) is a facial pain disorder characterized by intense and paroxysmal pain that

« Status trigeminal neuralgia »: Analysis of 39 cases and proposal for diagnostic criteria

Revue Neurologique (Paris) 2024 May 23:S0035-3787(24)00523-X. doi: 10.1016/j.neurol.2024.03.014. Online ahead of print. Z Poullet, S Redon, R Gravier-Dumonceau, A Donnet Abstract Objective: The aim of this descriptive study was to propose diagnostic criteria for acute exacerbation of trigeminal neuralgia (TN) based on the

Focal changes in alpha oscillations during short-term memorization of pain: a high-density electroencephalogram study with source localization

The European journal of neuroscience 2024 May;59(10):2778-2791.  doi: 10.1111/ejn.16317. Epub 2024 Mar 21. Argitxu Caldichoury, Luis Garcia-Larrea, Maud Frot Abstract Memories of painful events constitute the basis for assessing patients’ pain. This study explores the brain oscillatory activity during short-term memorization of a

Novel Scorpion Toxin ω-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via CaV3.3 and CaV3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain

International Journal of Molecular Sciences 2024 Apr 26;25(9):4745. doi: 10.3390/ijms25094745. Dan Wang, Volker Herzig, Zoltan Dekan, K Johan Rosengren, Colton D Payne, Md Mahadhi Hasan, Jiajie Zhuang, Emmanuel Bourinet, Lotten Ragnarsson, Paul F Alewood, Richard J Lewis  Abstract Venom peptides have evolved to target a wide range of membrane proteins

Triptan use in elderly over 65 years and the risk of hospitalization for serious vascular events

The Journal of Headache and Pain 2024 Apr 26;25(1):68. doi: 10.1186/s10194-024-01770-x. Phuong Thao Tran, Maryse Lapeyre-Mestre, Baricault Berangere, Michel Lanteri-Minet, Aurore Palmaro, Anne Donnet, Joëlle Micallef  Abstract Background: Several studies have focused on the use of triptan and the risk of acute vascular events but the

Discordance between pain specialists and patients on the perception of dependence on pain medication: A multi-center cross-sectional study

Therapie 2024 Apr 12:S0040-5957(24)00043-X doi: 10.1016/j.therap.2024.01.008. Online ahead of print. Anne Roussin, Zénab Cissé, Vanessa Rousseau, Guillaume Roche, Cécile Lestrade, Alexandre Cauchie, Noémie Delage, Anne Donnet, Elise Van Obberghen, Chantal Wood, Maryse Lapeyre-Mestre, Nathalie Cantagrel Abstract Aim: Patients with chronic non-cancer pain are referred to pain centres to improve their pain

Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice

The Journal of clinical investigation . 2024 Mar 19;134(9):e176474. doi: 10.1172/JCI176474. Manon Defaye , Amyaouch Bradaia, Nasser S Abdullah, Francina Agosti, Mircea Iftinca, Mélissa Delanne-Cuménal, Vanessa Soubeyre, Kristofer Svendsen, Gurveer Gill, Aye Ozmaeian, Nadine Gheziel, Jérémy Martin, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Lilian Basso, Emmanuel Bourinet, Isaac M Chiu, Christophe Altier Abstract Inflammation and pain are intertwined