Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous preventive treatments were unsuccessful: a randomised, double-blind, placebo-controlled, phase 3b study.

Lancet. 2018 Nov 24;392(10161):2280-2287. doi: 10.1016/S0140-6736(18)32534-0. Epub 2018 Oct 22. Reuter U1, Goadsby PJ2, Lanteri-Minet M3, Wen S4, Hours-Zesiger P5, Ferrari MD6, Klatt J5. Abstract BACKGROUND: A substantial proportion of patients with migraine does not respond to, or cannot tolerate,